Articles

Abstract. Exosomes are one of the most potent intercellular communicators, which are able to communicate with adjacent or distant cells. Exosomes deliver various bioactive molecules, including membrane receptors, proteins, mRNA and microRNA, to target cells and serve roles. Recent studies have demonstrated that exosomes may regulate the functions and diseases of the skin, which is…

Background: The use of growth factors in skin rejuvenation is emerging as a novel anti-aging treatment. While the role ofgrowth factors in wound healing is well established, their use in skin rejuvenation has only recently been to be studied andno controlled trials have been performed. Objective: We evaluated the anti-aging effects of secretory factors ofendothelial…

ABSTRACTGrowing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeuticentities, particularly in stem cell-related approaches, has underlined the need for standardizationand coordination of development efforts. Members of the International Society forExtracellular Vesicles and the Society for Clinical Research and Translation of Extracellular VesiclesSingapore convened a Workshop on this topic to discuss the opportunities…

AbstractA recent survey of practicing plastic surgeons showed that regenerative medicine is the current top interest of esthetic consumers worldwide. Patientsare frequently requesting correction of small regions, instead of opting for an all-encompassing procedure associated with prolonged recovery time. Thus, thefield of “microlifting” has emerged. This is a new approach in which minimally invasive procedures…